Biomolecular control group

Systems & Synthetic Biology at the University of Edinburgh

Our two locations: the Informatics Forum and the CH Waddington Building in Edinburgh.

what we do

Our team develops computational methods to study molecular processes in living cells. We use mathematics to understand natural networks and to design novel systems for biotechnology and biomedicine. We employ a wide range of methods, such as machine learning, control theory, stochastic analysis and network theory. Large parts of our work are in collaboration with Systems and Synthetic Biology labs in the UK and abroad.

You can read more about our work in this piece.

who we are

The group lead is Diego Oyarzún and includes research students and postdocs. Together we gather expertise in many disciplines like machine learning, mathematics, biochemistry and bioinformatics.

where we work

We are very lucky to be located at the School of Informatics and the School of Biological Sciences of the University of Edinburgh, in one of the most vibrant and stimulating European capitals. We are members of SynthSys, the Edinburgh Centre for Synthetic and Systems Biology.

recent papers


Jan 5, 2023 Evangelos’ paper on deep learning models of protein expression has been published in Nature Communications.
Dec 12, 2022 We are organising the first Turing Workshop in AI, Engineering Biology & Beyond, applications are open to join us 13-14 March 2023 in Edinburgh!
Dec 2, 2022 Arin was selected for a Data Study Group at the Alan Turing Institute in London, congrats!
Sep 29, 2022 Lilli won a 2022 Young Software Engineer of the Year Award for her work on machine learning for prediction of essential genes. Amazing achievement, congrats! Check her prize clip here from minute 7:00 onwards.
Sep 27, 2022 Charlotte is organizing an exciting meeting on Synthetic Biology in the Age of Machine Learning at the upcoming ICSB 2022 in Berlin.
Sep 16, 2022 A warm welcome to our new students in the team: Yuxin Shen (PhD), Vivek Manthana (Hons), Scott Florence (Hons), Chi-Shiun Yang (Hons).
Aug 1, 2022 Seb, Dom and Hans’ paper on variational autoencoders for SARS-CoV-2 vaccine design appeared at ICML 2022 in Baltimore.
Jun 9, 2022 Lilli’s paper on machine learning for prediction of essential genes will be published in the FOSBE 2022 conference in Boston.
Jun 6, 2022 We have launched The Science For Sustainability Hub, a unique initiative for research aimed at the UN Sustainable Development Goals.
Jun 1, 2022 Evangelos won a poster prize at the MOMI2022 conference in Nice, France. Congrats!