Biomolecular control group

Systems & Synthetic Biology at the University of Edinburgh

Our two locations: the Informatics Forum and the CH Waddington Building in Edinburgh.

what we do

Our team develops computational methods to study molecular processes in living cells. We use mathematics to understand natural networks and to design novel systems for biotechnology and biomedicine. We employ a wide range of methods, such as machine learning, control theory, stochastic analysis and network theory. Large parts of our work are in collaboration with Systems and Synthetic Biology labs in the UK and abroad.

who we are

The group lead is Diego Oyarzún and includes research students and postdocs. Together we gather expertise in many disciplines like machine learning, mathematics, biochemistry and bioinformatics.

where we work

We are very lucky to be located at the School of Informatics and the School of Biological Sciences of the University of Edinburgh, in one of the most vibrant European capitals. We are members of the Edinburgh Centre for Engineering Biology.

recent papers

news

Dec 1, 2024 Arin’s paper on single-cell metabolic oscillations is out in preprint - this is part of a great collaboration with the Swain lab.
Nov 25, 2024 Michal’s paper on risk-averse design of synthetic gene circuits is out in preprint - super nice collaboration with Michael Gutmann.
Nov 5, 2024 We have an exciting PhD position on AI for drug discovery against Chagas disease.
Oct 10, 2024 A very warm farewell to Ricardo, who has taken up a postdoctoral role at the Earlham Institute after a brilliant PhD!
Oct 1, 2024 We welcome five new members to our team: Nicola, Alperen, Cata, Pattie and Sam. A pleasure to have you with us!
Sep 30, 2024 Super congrats to Charlotte for winning the Best Talk Award at FOSBE 2024 in Corfu, Greece.
Sep 15, 2024 Very exciting to see that several team members have a busy schedule speaking at various conferences in the UK and abroad, including SynBio UK in Cambridge and Next-Generation Synthetic Biology in Belgium.
Jun 18, 2024 Our exciting Canada/USA/UK multidisciplinary collaboration on analyses of patient multimorbidity networks just got published in the J of Clinical Epidemiology.
Jun 10, 2024 Evangelos successfully passed his PhD viva - congrats Dr Nikolados! We say warmly say goodbye to one of the first members of our lab, onward and upward!
Jun 5, 2024 Hans’ work on fine-tuning ProteinMPNN to design sequences with low immunogenicity is out in preprint - really exciting work!