The aim of our research is to understand how the brain achieves and maintains function and stability throughout life. As in all biological systems, in the brain important things happen simultaneously on different scales, from the sub-cellular level to entire circuits and beyond, and from milliseconds to a lifetime. We address this problem through computational modelling and the analysis of neurophysiological data. Models help us to understand the interactions between these scales, and to interpret and augment experimental findings. Specifically, our work is currently in the following areas:
- Function, plasticity and homeostasis at the sub-cellular and cellular level
- Stability and function in networks of neurons
- Analysis of high-density multielectrode recordings
This work is currently funded by the EC grant RENVISION (2013-2016), and
research grants from the BBSRC and EPSRC.